产品货号:
Z29170
中文名称:
TRIP12抗体
英文名称:
Anti-TRIP12 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIP12 Antibody |
指标别名 | KIAA0045,TR interacting protein 12,TRIP 12,TRIP12 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF,ICC |
基因名称 | TRIP12 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRIP12 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human TRIP12.The immunogen is located within amino acids 1930 - 1980 of TRIP12. |
计算分子量 | 220kDa |
成分 | TRIP12 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRIP12 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner (1).TRIP12 (thyroid hormone receptor interactor 12) is an ATP-dependent E3 ubiquitin ligase involved in the human ubiquitin fusion degradation (UFD) pathway and also modulates the NEDD8 pathway (2,3).TRIP12 contains one WWE domain and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain suggested to contain a noncovalent ubiquitin-binding site (4).TRIP12 acts as a key regulator of DNA damage response and the ubiquitin ligase activity of TRIP12 is essential for mouse development (5). |
Uniprot ID | Q14669 |
基因名全称 | Thyroid hormone receptor interactor 12 |
蛋白名全称 | Thyroid hormone receptor interactor 12 |
推荐稀释比 | TRIP12 antibody can be used for detection of TRIP12 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.For immunocytochemistry start at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples;Immunocytochemistry in human samples;and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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